Gather all ingredients before starting (salsa, blackening spice and tilapia).
Season tilapia with blackening spice and set aside for up to 30 minutes before frying.
Melt butter and oil in a medium skillet over medium high heat until the mixture starts to bubble, 1-2 minutes.
Place tilapia fillets in the frying pan and fry each side for 2-3 minutes. Check before turning, the fish should be nicely browned and should have a bit of a crust. When the first side is done, fry the second side for another 2-3 minutes.
Serve the tilapia hot over plain white rice, sprinkle pineapple salsa over the top and around the plate.